Dr Amaral obtained her MD degree from Lisbon University in 2006, concurrent with her degree in Aeronautic Medicine from the Portuguese Air Force. Following her graduation, she pursued her general internship at CHLN and Hospital Pulido Valente in Lisbon in 2007, followed by Medical Oncology Internship in 2008. She is a board-certified Specialist in Medical Oncology since 2014.

In 2016, Dr Amaral embarked on her PhD journey at the renowned Skin Cancer Center in Tuebingen, Germany, working under the guidance of Prof. Claus Garbe. Her PhD thesis, titled "Progress in systemic therapy of advanced melanoma between 2011 and 2019," was successfully defended at the Nova Medical School in Lisbon in June 2021, earning her the distinction “Magna cum Laude”. Since 2021, she has assumed the position of Head of Translational Research at the Skin Cancer Center in Tuebingen, continuing her dedication to advancing the understanding and treatment of skin cancer.

Dr Amaral’s primary research focus revolves around predictive biomarkers for systemic therapy in advanced melanoma and prognostic and predictive biomarkers in early-stage melanoma.

She was nominated as head of the skin cancer clinical trials center in Tuebingen in January 2022, overseeing numerous phase I-III studies, including investigator-initiated trials. In addition, she is responsible for training medical residents within the center. In 2022 she received the recognition of board certified Specialist in Internal Medicine, Haematology and Oncology from the German medical association.

Dr Amaral serves as a lecturer at the Tuebingen University medicine faculty since 2022, guiding and mentoring medical students during their medical thesis. Dr Amaral also maintains active collaborations with various Portuguese medical universities, where she is invited as a guest lecturer.

Between 2020 and 2022, Dr Amaral served as the Chair of the ESMO (European Society for Medical Oncology) Young Oncologists Committee. Currently, she is member of the ESMO Melanoma and Other Skin Tumours Faculty and subject editor for melanoma and other skin cancers guidelines. Since January 2023 she is Chair of the ESMO Leadership Development Committee and serves as an ESMO Council Member.